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Neurobiological mechanisms of PNOS are not well understood. However, functional neuroimaging has implicated certain structures. Because PNES is considered a disorder a brain function, there has been a growing body of research to investigate functional brain changes in these patients. According to a 2024 literature review of patients with PNES who underwent brain imaging, three neuroanatomical locations were recurrently found to have functional (rather than structural) abnormalities as detailed in the table below. More research needs to be completed to further evaluate the pathophysiology of PNES. |
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Neurobiological mechanisms of PNES are not well understood. However, functional neuroimaging has implicated certain structures. Because PNES is considered a disorder of brain function, there has been a growing body of research to investigate functional brain changes in these patients. According to a 2024 literature review of patients with PNES who underwent brain imaging, three neuroanatomical locations were recurrently found to have functional (rather than structural) abnormalities as detailed in the table below. More research needs to be completed to further evaluate the pathophysiology of PNES. |