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In 2013, Gurira played a lead role in director [[Andrew Dosunmu]]'s independent drama film ''[[Mother of George]]'', which premiered at [[2013 Sundance Film Festival]]. Gurira received critical acclaim for her performance as a Nigerian woman struggling to live in the United States.[{{cite news|last1=Bell|first1=Nicholas|title=Mother of George – Review|url=http://www.ioncinema.com/reviews/mother-of-george-review|access-date=October 28, 2014|work=IonCinema|date=September 13, 2013|archive-date=February 21, 2018|archive-url=https://web.archive.org/web/20180221100126/https://www.ioncinema.com/reviews/mother-of-george-review|url-status=live}}][{{cite magazine|last1=Gleiberman|first1=Owen|title=Sundance: 'Lovelace' is a porn biopic that gets under your skin|url=http://insidemovies.ew.com/2013/01/23/linda-lovelace-bio-gets-under-your-skin/|access-date=October 28, 2014|magazine=Entertainment Weekly|date=January 23, 2013|archive-date=January 25, 2013|archive-url=https://web.archive.org/web/20130125235554/http://insidemovies.ew.com/2013/01/23/linda-lovelace-bio-gets-under-your-skin/|url-status=live}}] In June 2013, Gurira won the Jean-Claude Gahd Dam award at the 2013 [[Guys Choice Awards]].[{{cite web|title=Jean-Claude Van Dam|url=http://www.spike.com/guys-choice/jean-claude-gahd-dam|work=Spike|access-date=June 12, 2013|archive-url=https://web.archive.org/web/20130527151256/http://www.spike.com/guys-choice/jean-claude-gahd-dam|archive-date=May 27, 2013|url-status=dead}}] The film was featured in [[IndieWire|Indiewire's]] 100 Best Movies of the Decade list and she was called a "stand out" in the film.[{{Cite web |last=Zilko |first=David Ehrlich,Eric Kohn,Kate Erbland,Anne Thompson,Zack Sharf,Chris O'Falt,Tambay Obenson,Christian Blauvelt,Leah Lu,Christian |date=2019-07-22 |title=The 100 Best Movies of the Decade |url=https://www.indiewire.com/gallery/best-movies-of-2010s-decade/ |access-date=2025-12-11 |website=IndieWire |language=en-US}}] |
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In 2013, Gurira played a lead role in director [[Andrew Dosunmu]]'s independent drama film ''[[Mother of George]]'', which premiered at [[2013 Sundance Film Festival]]. Gurira received critical acclaim for her performance as a Nigerian woman struggling to live in the United States.[{{cite news|last1=Bell|first1=Nicholas|title=Mother of George – Review|url=http://www.ioncinema.com/reviews/mother-of-george-review|access-date=October 28, 2014|work=IonCinema|date=September 13, 2013|archive-date=February 21, 2018|archive-url=https://web.archive.org/web/20180221100126/https://www.ioncinema.com/reviews/mother-of-george-review|url-status=live}}][{{cite magazine|last1=Gleiberman|first1=Owen|title=Sundance: 'Lovelace' is a porn biopic that gets under your skin|url=http://insidemovies.ew.com/2013/01/23/linda-lovelace-bio-gets-under-your-skin/|access-date=October 28, 2014|magazine=Entertainment Weekly|date=January 23, 2013|archive-date=January 25, 2013|archive-url=https://web.archive.org/web/20130125235554/http://insidemovies.ew.com/2013/01/23/linda-lovelace-bio-gets-under-your-skin/|url-status=live}}] In June 2013, Gurira won the Jean-Claude Gahd Dam award at the 2013 [[Guys Choice Awards]].[{{cite web|title=Jean-Claude Van Dam|url=http://www.spike.com/guys-choice/jean-claude-gahd-dam|work=Spike|access-date=June 12, 2013|archive-url=https://web.archive.org/web/20130527151256/http://www.spike.com/guys-choice/jean-claude-gahd-dam|archive-date=May 27, 2013|url-status=dead}}] The film was featured in [[IndieWire|Indiewire's]] 100 Best Movies of the Decade list and she was called a "stand out" in the film.[{{Cite web |last=Zilko |first=David Ehrlich,Eric Kohn,Kate Erbland,Anne Thompson,Zack Sharf,Chris O'Falt,Tambay Obenson,Christian Blauvelt,Leah Lu,Christian |date=2019-07-22 |title=The 100 Best Movies of the Decade |url=https://www.indiewire.com/gallery/best-movies-of-2010s-decade/ |access-date=2025-12-11 |website=IndieWire |language=en-US}}] |
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Gurira played rapper [[Tupac Shakur]]'s mother, [[Afeni Shakur]], in ''[[All Eyez on Me (film)|All Eyez on Me]]'', a 2017 biopic about the rap star.[{{Cite web|title = Walking Dead's Danai Gurira Cast as Tupac Shakur's Mother|url = https://www.ign.com/articles/2016/01/12/walking-deads-danai-gurira-cast-as-tupac-shakurs-mother|work = IGN|date = January 11, 2016|access-date = January 12, 2016|first = Nicole|last = Carpenter|archive-date = January 12, 2016|archive-url = https://web.archive.org/web/20160112013117/http://www.ign.com/articles/2016/01/12/walking-deads-danai-gurira-cast-as-tupac-shakurs-mother|url-status = live}}] Her performance gathered praise with [[IndieWire]] saying "Danai Gurira- as Tupac's beloved mother Afeni comes out swinging during the film's opening sequence and never lets up, believably burning right through the screen, conjuring the kind of passion the rest of the film lacks. If anyone makes off with a movie star turn in "All Eyez on Me," it's Walking Dead" star Gurira." [{{Cite web |last=Erbland |first=Kate |date=2017-06-15 |title=‘All Eyez on Me’ Review: Tupac Shakur’s Complicated Life Deserves More Than This Sprawling Biopic |url=https://www.indiewire.com/features/general/all-eyez-on-me-review-tupac-shakur-biopic-1201842385/ |access-date=2026-04-24 |website=IndieWire |language=en-US}}][[The Hollywood Reporter]] says "Gurira gives great fiery intensity"[{{Cite web |last=Dalton |first=Stephen |date=2017-06-15 |title=‘All Eyez on Me’: Film Review |url=https://www.hollywoodreporter.com/movies/movie-reviews/all-eyez-me-review-1013778/ |access-date=2026-04-24 |website=The Hollywood Reporter |language=en-US}}] and [[Variety (magazine)|Variety]] in their review said "Danai Gurira(who would have been perfect as Nina Simone), Gurira makes her a ruthlessly intelligent analyst of the white power structure who is nevertheless consumed by a rage that has no outlet." For this movie she received a [[49th NAACP Image Awards|NAACP Image awards]] nomination for Outstanding Actress in a Motion Picture.[{{Cite web |author= |date=2017-11-20 |title=NAACP Image Awards: 'Marshall,' 'Get Out,' 'Girls Trip' Dominate Film Nominations |url=https://www.hollywoodreporter.com/lists/2018-naacp-image-award-nominations-complete-list-1057758/outstanding-actress-in-a-motion-picture-3/ |access-date=2025-02-27 |website=The Hollywood Reporter |language=en-US}}] |
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Gurira played rapper [[Tupac Shakur]]'s mother, [[Afeni Shakur]], in ''[[All Eyez on Me (film)|All Eyez on Me]]'', a 2017 biopic about the rap star.[{{Cite web|title = Walking Dead's Danai Gurira Cast as Tupac Shakur's Mother|url = https://www.ign.com/articles/2016/01/12/walking-deads-danai-gurira-cast-as-tupac-shakurs-mother|work = IGN|date = January 11, 2016|access-date = January 12, 2016|first = Nicole|last = Carpenter|archive-date = January 12, 2016|archive-url = https://web.archive.org/web/20160112013117/http://www.ign.com/articles/2016/01/12/walking-deads-danai-gurira-cast-as-tupac-shakurs-mother|url-status = live}}] Her performance gathered praise with [[IndieWire]] saying "Danai Gurira- as Tupac's beloved mother Afeni comes out swinging during the film's opening sequence and never lets up, believably burning right through the screen, conjuring the kind of passion the rest of the film lacks. If anyone makes off with a movie star turn in "All Eyez on Me," it's Walking Dead" star Gurira." [{{Cite web |last=Erbland |first=Kate |date=2017-06-15 |title=‘All Eyez on Me’ Review: Tupac Shakur’s Complicated Life Deserves More Than This Sprawling Biopic |url=https://www.indiewire.com/features/general/all-eyez-on-me-review-tupac-shakur-biopic-1201842385/ |access-date=2026-04-24 |website=IndieWire |language=en-US}}][[The Hollywood Reporter]] says "Gurira gives great fiery intensity"[{{Cite web |last=Dalton |first=Stephen |date=2017-06-15 |title=‘All Eyez on Me’: Film Review |url=https://www.hollywoodreporter.com/movies/movie-reviews/all-eyez-me-review-1013778/ |access-date=2026-04-24 |website=The Hollywood Reporter |language=en-US}}] and [[Variety (magazine)|Variety]] in their review said "Afeni Shakur is played by Danai Gurira(who would have been perfect as Nina Simone), Gurira makes her a ruthlessly intelligent analyst of the white power structure who is nevertheless consumed by a rage that has no outlet."[{{Cite web |last=Gleiberman |first=Owen |date=2017-06-15 |title=Film Review: ‘All Eyez on Me’ |url=https://variety.com/2017/film/reviews/all-eyez-on-me-review-tupac-shakur-1202467109/ |access-date=2026-04-24 |website=Variety |language=en-US}}] For this movie she received a [[49th NAACP Image Awards|NAACP Image awards]] nomination for Outstanding Actress in a Motion Picture.[{{Cite web |author= |date=2017-11-20 |title=NAACP Image Awards: 'Marshall,' 'Get Out,' 'Girls Trip' Dominate Film Nominations |url=https://www.hollywoodreporter.com/lists/2018-naacp-image-award-nominations-complete-list-1057758/outstanding-actress-in-a-motion-picture-3/ |access-date=2025-02-27 |website=The Hollywood Reporter |language=en-US}}] |
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In 2020, she signed a deal with ABC Studios.[{{Cite web|last=Otterson|first=Joe|date=2020-02-20|title=Danai Gurira Inks Overall Deal With ABC Studios|url=https://variety.com/2020/tv/news/danai-gurira-overall-deal-abc-studios-1203509281/|access-date=2021-02-01|website=Variety|language=en-US|archive-date=February 27, 2021|archive-url=https://web.archive.org/web/20210227135551/https://variety.com/2020/tv/news/danai-gurira-overall-deal-abc-studios-1203509281/|url-status=live}}] |
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In 2020, she signed a deal with ABC Studios.[{{Cite web|last=Otterson|first=Joe|date=2020-02-20|title=Danai Gurira Inks Overall Deal With ABC Studios|url=https://variety.com/2020/tv/news/danai-gurira-overall-deal-abc-studios-1203509281/|access-date=2021-02-01|website=Variety|language=en-US|archive-date=February 27, 2021|archive-url=https://web.archive.org/web/20210227135551/https://variety.com/2020/tv/news/danai-gurira-overall-deal-abc-studios-1203509281/|url-status=live}}] |